Klebsiella pneumoniae: epidemiology and analysis of risk factors for infections caused by resistant strains / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1158-1162, 2002.
Article
in English
| WPRIM
| ID: wpr-340367
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the epidemiology of hospital and community-acquired infections caused by Klebsiella pneumoniae (K. pneumoniae) and risk factors for infections caused by resistant strains.</p><p><b>METHODS</b>A retrospective observational study was performed to analyze the relationship between antimicrobial use and bacterial resistance.</p><p><b>RESULTS</b>A K. pneumoniae infection was diagnosed in 0.47% of patients (169 of 36 179) admitted to the hospital between 1 March 1999 and 31 August 2000. Of the 169 isolates, 166 (98.2%) were resistant to at least one antimicrobial and 91.1% (154/169) to two or more antibiotics. 98% were resistant to ampicillin, 77% to piperacillin, 64% to cephalothin, 60% to ampicillin/sulbactam, 59% to cefoperazone, 57% to cefazolin, 55% to cefuroxime, 51% to TMP-SMZ, 51% to tobramycin, 50% to gentamicin, 49% to aztreonam, cefetaxime and ceftriaxone respectively, 47% to ceftazidime, 47% to cefepime, 46% to ciprofloxacin, 46% to ticarcillin/clavulanate, 44% to amikacin, 38% to cefoxitin, 22% to piperacillin/tazobactam, while all strains were tested susceptible to imipenem.</p><p><b>CONCLUSIONS</b>Prior receipt of amtimicrobial therapy was significantly associated with infection caused by a resistant organism and most strains were resistant to multiple antibiotics.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Klebsiella Infections
/
Epidemiology
/
Risk Factors
/
Drug Resistance, Bacterial
/
Drug Therapy
/
Klebsiella pneumoniae
Type of study:
Etiology study
/
Observational study
/
Risk factors
/
Screening study
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Chinese Medical Journal
Year:
2002
Type:
Article
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