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Effects of radiation injury on peripheral blood and liver NO concentration in mice / 南方医科大学学报
Journal of Southern Medical University ; (12): 1405-1406, 2008.
Article in Chinese | WPRIM | ID: wpr-340810
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of radiation injury on nitric oxide (NO) concentration in mouse peripheral blood and liver.</p><p><b>METHODS</b>NIH mice were subjected to gamma-ray exposure at 9.0 Gy and transferred immediately in room temperature condition. NO concentrations in the liver and peripheral blood were examined before and at different time points after the exposure.</p><p><b>RESULTS</b>Compared to that before exposure, NO concentration in the peripheral blood and liver significantly increased after gamma-ray exposure. NO concentration in the peripheral blood began to increase 3 h after the exposure, but that in the liver increased till 6 h after the exposure.</p><p><b>CONCLUSION</b>Radiation can cause the increase of NO concentration in the peripheral blood and liver, but different tissues may exhibit different response intensities to radiation.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Radiation Effects / Radiation Injuries, Experimental / Time Factors / Blood / Gamma Rays / Liver / Metabolism / Nitric Oxide Limits: Animals Language: Chinese Journal: Journal of Southern Medical University Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Radiation Effects / Radiation Injuries, Experimental / Time Factors / Blood / Gamma Rays / Liver / Metabolism / Nitric Oxide Limits: Animals Language: Chinese Journal: Journal of Southern Medical University Year: 2008 Type: Article