Effects of radiation injury on peripheral blood and liver NO concentration in mice / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1405-1406, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-340810
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of radiation injury on nitric oxide (NO) concentration in mouse peripheral blood and liver.</p><p><b>METHODS</b>NIH mice were subjected to gamma-ray exposure at 9.0 Gy and transferred immediately in room temperature condition. NO concentrations in the liver and peripheral blood were examined before and at different time points after the exposure.</p><p><b>RESULTS</b>Compared to that before exposure, NO concentration in the peripheral blood and liver significantly increased after gamma-ray exposure. NO concentration in the peripheral blood began to increase 3 h after the exposure, but that in the liver increased till 6 h after the exposure.</p><p><b>CONCLUSION</b>Radiation can cause the increase of NO concentration in the peripheral blood and liver, but different tissues may exhibit different response intensities to radiation.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiation Effects
/
Radiation Injuries, Experimental
/
Time Factors
/
Blood
/
Gamma Rays
/
Liver
/
Metabolism
/
Nitric Oxide
Limits:
Animals
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2008
Type:
Article
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