A long term follow-up study of the skull base chordomas / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1118-1120, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-340850
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the prognostic features of the skull base chordomas treated with neurosurgical operations.</p><p><b>METHODS</b>One hundred and six patients of skull base chordomas were enrolled by means of telephone, letter and out-patient recheck who presented between May 1993 and June 2005. They were scored by Karnofsky Performance Scale (KPS) during admission respectively, before period of discharge and follow-up. SPSS Life-table method was used to calculate the recurrent rates and survival rates.</p><p><b>RESULTS</b>Seventy-nine patients were followed for 10-158 months. The average period was 63.9 months. Survival rates of 1, 3, 5 and 10 year were 87.2%, 79.4%, 67.6% and 59.5%, meanwhile recurrent rates of 1, 3, 5 and 10 years were 19.1%, 34.7%, 52.9% and 88.3% respectively. The mean KPS on admission, before discharge and follow-up were 71.0, 72.5 and 67.1 respectively, which demonstrated the significant differences between the before discharge item and the follow-up.</p><p><b>CONCLUSIONS</b>The prognosis of the skull base chordomas was poor. The recurrent rate was ascending year by year, meanwhile the survival rate was descending and 8 years later the tendency became gently. Neurosurgical treatments can improve majority long-term qualities, so they should be viewed as the first treatment choice.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Prognosis
/
General Surgery
/
Chordoma
/
Survival Analysis
/
Retrospective Studies
/
Follow-Up Studies
/
Treatment Outcome
/
Skull Base Neoplasms
/
Neoplasm Recurrence, Local
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS