A new model for survival assessment based on the Chinese liver transplantation patients with hepatocellular carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1023-1026, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-340868
ABSTRACT
<p><b>OBJECTIVE</b>To establish a new model for liver transplantation recipients with hepatocellular carcinoma (HCC) and validate the feasibility of it.</p><p><b>METHODS</b>From February 1999 to June 2005, clinical data of 130 liver cancer patients who accepted liver transplantation were collected. Screening the pretransplant factors correlated with post-transplant survival using COX proportional-hazards regression, and establishing the assessment model. Finally, the area under the receiver operating characteristic curve (AUC ROC) were used to compare the validity of the new model with MELD.</p><p><b>RESULTS</b>Screened by the COX model, serum concentrations of alkaline phosphatase, alphafetoprotein, sodium and the number of tumor nodule were significantly related with post-transplant survival. The new model with these four variables had greater ability to assess post-transplant recipients' outcomes, however, the MELD had not evaluation capacity.</p><p><b>CONCLUSION</b>The established new model has a better ability to assess the risk of post-transplant mortality.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sodium
/
General Surgery
/
Blood
/
Alpha-Fetoproteins
/
Proportional Hazards Models
/
Survival Analysis
/
China
/
Feasibility Studies
/
Reproducibility of Results
/
Liver Transplantation
Type of study:
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2007
Type:
Article
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