Phenotypic modulation of vascular smooth muscle cells in diabetes mellitus and intervention of traditional Chinese medicines / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4723-4727, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-341827
ABSTRACT
Proliferation and migration of vascular smooth muscle cells (VSMC) are common pathological features of diabetic vascular complications,such as atherosclerosis and hypertension. Phenotypic modulation of VSMC is the basis for VSMC proliferation and migration. Therefore, studies on VSMC phenotypic modulation and its mechanisms in diabetes mellitus were of important significance to the prevention and therapy of diabetic vascular complications. This paper introduces VSMC phenotypic modulation and the underlying mechanisms in diabetes mellitus, and summarizes advance of studies on traditional Chinese medicine intervention upon VSMC phenotypic modulation, so as to provide reference for preventing and treating diabetic vascular complications with traditional Chinese medicines.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Phenotype
/
Drugs, Chinese Herbal
/
Cell Movement
/
Myocytes, Smooth Muscle
/
Therapeutic Uses
/
Cell Proliferation
/
Diabetes Mellitus
/
Drug Therapy
/
Atherosclerosis
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2014
Type:
Article
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