Experimental study on attachment of bacillus Calmette-Guerin to bladder wall with different types of injury / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 65-67, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-341940
ABSTRACT
<p><b>OBJECTIVE</b>To investigate whether different types of injury on bladder wall can influence bacillus Calmette-Guerin (BCG) attachment.</p><p><b>METHODS</b>The bladder mucosa of 24 rabbits were treated by electrocautery,cryocautery and incision on left lateral wall, right lateral wall and posterior wall, respectively. Then radiolabeled BCG ((3)H-BCG) was instilled into bladder. Two hours latter, the injured bladder wall with different methods and non-injured wall (anterior wall of bladder) were surgically removed and digested. The quantity of BCG of each specimen was determined by liquid scintillation counter.</p><p><b>RESULT</b>The quantity of BCG attachment to bladder wall with different injuries was significantly higher than that of non-injured wall (P<0.001), meanwhile there was no statistically difference among the BCG levels of different injury types (P>0.05).</p><p><b>CONCLUSION</b>BCG attachment is not influenced by different types of injury on the bladder wall.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Wounds and Injuries
/
Urinary Bladder
/
Bacterial Adhesion
/
Microbiology
/
Mycobacterium bovis
Limits:
Animals
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2004
Type:
Article
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