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Essential genes, minimal genome and synthetic cell of bacteria: a review / 生物工程学报
Chinese Journal of Biotechnology ; (12): 540-549, 2012.
Article in Chinese | WPRIM | ID: wpr-342463
ABSTRACT
Single-cell prokaryotes represent a simple and primitive cellular life form. The identification of the essential genes of bacteria and the minimal genome for the free-living cellular life could provide insights into the origin, evolution, and essence of life forms. The principles, methodology, and recent progresses in the identification of essential genes and minimal genome and the creation of synthetic cells are reviewed and particularly the strategies for creating the minimal genome and the potential applications are introduced.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Bacteria / Genome, Bacterial / Genes, Essential / Metabolic Networks and Pathways / Synthetic Biology / Artificial Cells / Genome Size / Genetics / Metabolism / Methods Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Bacteria / Genome, Bacterial / Genes, Essential / Metabolic Networks and Pathways / Synthetic Biology / Artificial Cells / Genome Size / Genetics / Metabolism / Methods Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2012 Type: Article