Your browser doesn't support javascript.
loading
Impact of depressed left ventricular function on outcomes in patients with three-vessel coronary disease undergoing percutaneous coronary intervention / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 609-614, 2013.
Article in English | WPRIM | ID: wpr-342530
ABSTRACT
<p><b>BACKGROUND</b>Patients with multivessel coronary artery disease and depressed left ventricular ejection fraction (LVEF) represent a high risk group of patients for coronary revascularization. There are limited data on percutaneous coronary intervention treatment in this population.</p><p><b>METHODS</b>Among a cohort of 4335 patients with three-vessel disease with or without left main disease undergoing percutaneous coronary intervention, 191 patients had LVEF < 40% (low ejection fraction (EF)) and 4144 patients had LVEF ≥ 40%. In-hospital and long-term outcomes were examined according to LVEF.</p><p><b>RESULTS</b>The estimated two-year rates of major adverse cardiac events, cardiac death, and myocardial infarction were significantly higher in the low EF group (19.64% vs. 8.73%, Log-rank test P < 0.01; 10.30% vs. 1.33%, Log-rank test P < 0.01, and 10.32% vs. 2.28%, Log-rank test P < 0.01 respectively), but there was no difference in the rates of target vessel revascularization (6.18% vs. 6.11%, Log-rank test P = 0.96). Using the Cox proportional hazard models, LVEF < 40% was a significant risk factor for cardiac death, myocardial infarction, and major adverse cardiac events (OR (95%CI) 4.779 (2.369 - 9.637), 2.673 (1.353 - 5.282), and 1.827 (1.187 - 2.813) respectively), but was not a statistically significant risk factor for target vessel revascularization (OR (95%CI) 1.094 (0.558 - 2.147)).</p><p><b>CONCLUSION</b>Among patients undergoing percutaneous coronary intervention for multivessel coronary artery disease, left ventricular dysfunction remains associated with further risk of cardiac death in-hospital and during long-term follow-up.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Therapeutics / Angioplasty, Balloon, Coronary / Ventricular Function, Left / Coronary Disease Type of study: Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Language: English Journal: Chinese Medical Journal Year: 2013 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Therapeutics / Angioplasty, Balloon, Coronary / Ventricular Function, Left / Coronary Disease Type of study: Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Language: English Journal: Chinese Medical Journal Year: 2013 Type: Article