Studies on chemical constituents of Uvaria macrophylia / 药学学报

ABSTRACT

<p><b>AIM</b>To study the chemical constituents from Uvaria macrophylla Roxb. (Annonaceae).</p><p><b>METHODS</b>Various chromatography techniques were used to separate and purify the constituents. Their structures were elucidated by UV, IR, MS, 1HNMR, 13CNMR, 1H-1H COSY, HMQC and HMBC spectral analysis.</p><p><b>RESULTS</b>Seven compounds have been isolated from the CHCl3 extract of the roots of the U. macrophylla. They were identified as macrophyllin (1), onysilin (2), taraxerol (3), 3,5-dimethoxy benzyl benzoic acid ester (4), benzoic acid (5), beta-sitosterol (6) and daucosterol (7).</p><p><b>CONCLUSION</b>Compound 1 is a new compound. Compounds 2-7 were obtained from this plant for the first time.</p>