Current situation of researches on the molecule mechanism of hormone refractory prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 551-554, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-343573
ABSTRACT
Most cases of prostate cancer become hormone refractory after 12 to 18 months of androgen deprivation therapy. The etiology of the disease is thought to be multifactorial, associated with genetic, dietary, and environmental factors. The article reviews the current situation of researches at home and abroad on the molecule mechanism of hormone refractory. It expounds the influence of the androgen receptor and its genetic mutation, apoptosis and the gene changes of p53, p21, EphB2 on prostate cancer. It is hoped to be of some directive value for the studies of prostate cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Prostatic Neoplasms
/
Receptors, Androgen
/
Oncogene Protein p21(ras)
/
Genes, p53
/
Apoptosis
/
Receptor, EphB2
/
Drug Therapy
/
Genetics
Type of study:
Practice guideline
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2006
Type:
Article
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