Comparison between the results of ICSI with fresh and with frozen-thawed sperm obtained by PESA to treat azoospermia / 中华男科学杂志
National Journal of Andrology
;
(12): 443-449, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-343600
ABSTRACT
<p><b>OBJECTIVE</b>Retrospective study of the results of ICSI (intracytoplasmic sperm insemination) with frozen sperm obtained by PESA (percutaneous epididymal sperm aspiration) was performed in 27 patients.</p><p><b>METHODS</b>With conventional freezing method, sperm from diagnosing PESA and the remaining motile sperm after treating cycle were frozen. After frozen-thawed and ICSI process, fertilization rate, implantation rate, clinical pregnancy rate were compared and other outcomes including pregnant combinations and parameters of newborns of experimental group (which used frozen-thawed sperm) and control group (which used fresh PESA sperm) were analyzed respectively.</p><p><b>RESULTS</b>One hundred and sixty three and 1 157 oocytes of stage M II were injected respectively in the experimental group (15 cycles) and control group (100 cycles), and fertilization rate of experimental group was prominently higher than that of control group (84.05% vs 73.29%, P < 0.05), while implantation rate and clinical pregnancy rate were of no difference from the control, respectively (23.07% vs 15.73%; 53.33% vs 37.00%, P > 0.05). The differences in newborn's weights between two groups were of no statistical significance (P > 0.05). In the experimental group, eight clinical pregnancies were achieved including 5 live deliveries and 3 ongoing pregnancies, 37 clinical pregnancies including 30 deliveries with only 1 fetal death, 3 ongoing pregnancies and 4 abortions in the control group. Neither vital pregnant combinations nor neonate malformations were found in both groups.</p><p><b>CONCLUSION</b>ICSI using frozen-thawed sperm obtained by PESA is an economic effective and safe method to treat azoospermia. Recovering rates of frozen sperm form PESA should be further increased.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Semen Preservation
/
Therapeutics
/
Pregnancy Outcome
/
Case-Control Studies
/
Retrospective Studies
/
Pregnancy Rate
/
Sperm Injections, Intracytoplasmic
/
Azoospermia
/
Methods
Type of study:
Observational study
Limits:
Female
/
Humans
/
Male
/
Pregnancy
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2006
Type:
Article
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