Diagnosis and differential diagnosis of airway-centered interstitial fibrosis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 99-102, 2005.
Article
in Zh
| WPRIM
| ID: wpr-343759
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To describe a form of interstitial lung disease pathologically characterized by small airway-centered interstitial fibrosis (ACIF).</p><p><b>METHODS</b>We analyzed the clinical, pulmonary functional, radiographic, and histologic characteristics of one ACIF case in Peking Union Medical College Hospital and reviewed 12 cases in literatures.</p><p><b>RESULTS</b>Clinically, patients presented with chronic cough and progressive dyspnea. Pulmonary function tests showed restrictive ventilatory pattern. Bronchoalveolar lavage showed a mild increase in lymphocytes in most cases. Chest radiography revealed diffuse reticulonodular infiltrates, with thickening of the bronchial walls and surrounding fibrosis. The key finding in histopathology was a distinctive pattern of ACIF centered on membranous and respiratory bronchioles.</p><p><b>CONCLUSIONS</b>ACIF is a disease that do not fit into any known category of interstitial lung disease. Whether it is a unique disease remains to be determined.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Pulmonary Fibrosis
/
Respiratory Function Tests
/
Biopsy
/
Bronchi
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Diagnostic Imaging
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Tomography, X-Ray Computed
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Diagnosis
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Diagnosis, Differential
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Lung
Type of study:
Diagnostic_studies
Limits:
Adult
/
Humans
/
Male
Language:
Zh
Journal:
Acta Academiae Medicinae Sinicae
Year:
2005
Type:
Article