A new erythrodiol triterpene fatty ester from Scorzonera mongolica / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1258-1261, 2009.
Article
in English
| WPRIM
| ID: wpr-344098
ABSTRACT
Two erythrodiol triterpene fatty esters, 3beta-dodecanoyl erythrodiol (1) and 3beta-tetradecanoyl erythrodiol (2), were isolated from Scorzonera mongolica. Their structures were elucidated on the basis of IR, MS and extensive 2D NMR spectroscopic analysis. Compound 1 was identified to be a new compound and 2 was confirmed to be a new natural compound. Their antitumor effects in vitro were evaluated with MTT and SRB assays, but compounds 1 and 2 only showed moderate cytotoxicities on A-549 cell line.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Plants, Medicinal
/
Triterpenes
/
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Molecular Structure
/
Leukemia P388
/
Chemistry
/
Carcinoma, Hepatocellular
Type of study:
Prognostic study
Limits:
Animals
/
Humans
Language:
English
Journal:
Acta Pharmaceutica Sinica
Year:
2009
Type:
Article
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