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A new erythrodiol triterpene fatty ester from Scorzonera mongolica / 药学学报
Acta Pharmaceutica Sinica ; (12): 1258-1261, 2009.
Article in English | WPRIM | ID: wpr-344098
ABSTRACT
Two erythrodiol triterpene fatty esters, 3beta-dodecanoyl erythrodiol (1) and 3beta-tetradecanoyl erythrodiol (2), were isolated from Scorzonera mongolica. Their structures were elucidated on the basis of IR, MS and extensive 2D NMR spectroscopic analysis. Compound 1 was identified to be a new compound and 2 was confirmed to be a new natural compound. Their antitumor effects in vitro were evaluated with MTT and SRB assays, but compounds 1 and 2 only showed moderate cytotoxicities on A-549 cell line.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Plants, Medicinal / Triterpenes / Drugs, Chinese Herbal / Magnetic Resonance Spectroscopy / Molecular Structure / Leukemia P388 / Chemistry / Carcinoma, Hepatocellular Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: Acta Pharmaceutica Sinica Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Plants, Medicinal / Triterpenes / Drugs, Chinese Herbal / Magnetic Resonance Spectroscopy / Molecular Structure / Leukemia P388 / Chemistry / Carcinoma, Hepatocellular Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: Acta Pharmaceutica Sinica Year: 2009 Type: Article