Progress in genetic research on psoriatic arthritis / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 606-610, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-344211
ABSTRACT
Psoriatic arthritis is a form of inflammatory arthritis found among patients with psoriasis, which can lead to pain, swelling or stiffness in one or more joints and even movement disorders. Epidemiological studies have shown a higher heritability for psoriatic arthritis compared with psoriasis vulgaris. With the evolvement of DNA sequencing, many genes have been associated with psoriasis vulgaris and psoriatic arthritis, which included MHC, TNF, LCE, IL23R, IL12B, TRAF3IP2 and TNFAIP3, though some, such as MHC, IL-13 and PTPN22, have been specifically associated with psoriatic arthritis. These studies have laid a foundation for risk prediction, diagnosis and drug development for psoriatic arthritis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psoriasis
/
Arthritis, Psoriatic
/
Genetic Predisposition to Disease
/
Polymorphism, Single Nucleotide
/
Genetic Research
/
Genetics
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2017
Type:
Article
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