Chemical constituents from Xanthium mongolicum / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of Xanthium mongolicum.</p><p><b>METHOD</b>The compounds were isolated with column chromatography. The structures were determined by spectroscopic techniques.</p><p><b>RESULT</b>Eight compounds were isolated from X. mongolicum, four compounds are sesquiterpene lactones, two compounds are triterpenes and two compounds are lignins. Their structure elucidated as xanthatin (1), xanthinosin (2), 11alpha, 13-dihydroxanthatin (3), atractylenolide III (4), oleanolic acid (5), ursolic acid (6), lignocellulose (7), balanophonin (8).</p><p><b>CONCLUSION</b>Compounds 3-8 were isolated from this plant for the first time. Sesquiterpene lactones (1-3) had shown the induction hindrance activeness of the (ICAM-1), but the activitiy of 3 was weaker.</p>