Comparison of the efficacy and safety of compound carraghenates cream and compound carraghenates suppository in the treatment of mixed hemorrhoids / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 220-222, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-345202
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate and compare the efficacy and safety of titanoreine cream with compound carraghenates suppository in the treatment of mixed hemorrhoids.</p><p><b>METHODS</b>Two hundred and fifty-two patients with mixed hemorrhoids were enrolled in this randomized,open, multicentral trial. Patients applied titanoreine cream (study group, n=133) or compound carraghenates suppository (control group, n=119). The symptomatic relief including pain,bleeding and edema was evaluated by scoring system at 30 minutes, 3 hours, 6 hours, 1 day, 2 days, 3 days, 4 days, 6 days after administration.</p><p><b>RESULTS</b>Symptoms were significantly improved in both groups (87.3%, 94.8%, respectively) excepting symptom of pain relief, but there was no significant difference between two groups (P > 0.05). The pain scores were lower at every observing point in the study group than those in the control group (P< 0.05). The proportions of the patients with pain relief and all symptoms relief were both higher in the study group than that in the control group at 30 min, 3 h after drug used (both P< 0.01). No side effect was found during the triad.</p><p><b>CONCLUSION</b>Titanoreine cream has predominance of relieving pain and response time compared with compound carraghenates suppository, but other effects on mixed hemorrhoid are similar between the two groups.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ointments
/
Safety
/
Suppositories
/
Titanium
/
Zinc Oxide
/
Carrageenan
/
Therapeutic Uses
/
Drug Combinations
/
Drug Therapy
/
Hemorrhoids
Type of study:
Controlled clinical trial
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2005
Type:
Article
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