Progress on establishment of animal model of osteoarthritis by intra-articular injection / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 90-95, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-345265
ABSTRACT
Osteoarthritis (Osteoarthritis, OA) is a common clinical degenerative joint disease with increased incidence rate in recent years. Animal experiment is one of the important ways to explore pathogenesis and treatment of OA, while induced animal model is the most important part in animal experiment. Intra-articular injection of drugs is a classical method for establishing animal model of OA. Choose of animal should follows the principle of correlation, appropriateness and practicability, injections should perform in accordance with experimental purposes and subject, detections means and evaluation methods also should corresponding to experimental reality. The gold standard of OA animal model and intra-articular injections has not build, need further study.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoarthritis
/
Cytokines
/
Diagnosis
/
Disease Models, Animal
/
Allergy and Immunology
/
Injections, Intra-Articular
Type of study:
Diagnostic study
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2015
Type:
Article
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