Advance in research on the genetic etiology of spontaneous intracerebral hemorrhage / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 702-707, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-345375
ABSTRACT
Spontaneous intracerebral hemorrhage (SICH) is a form of brain parenchymal hemorrhage caused by a variety of non-traumatic reasons, resulting in cerebral artery, veins or capillaries rupture. The etiology of SICH is variable, with hypertensive intracerebral hemorrhage being the most common, accounting for 60% ~ 81% of all cases. Cerebral amyloid angiopathy, drug use related hemorrhage, Moyamoya disease are also important causes of SICH. Previous studies showed that genetic factors play an important role in the pathogenesis of SICH. Here the genetic mechanisms of SICH and classification of its etiology are reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Genetic Variation
/
Cerebral Hemorrhage
/
Genetic Predisposition to Disease
/
Polymorphism, Single Nucleotide
/
Biomedical Research
/
Diagnosis
/
Genetics
/
Genotype
/
Methods
/
Mutation
Type of study:
Diagnostic study
/
Etiology study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2016
Type:
Article
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