The drug-resistant mechanism of clinical non-fermenting bacilli producing IMP-1 metalloenzyme / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 876-879, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-346051
ABSTRACT
A total of 50 clinical imipenem-resistant isolates of Pseudomonas aeruginosa and Acinetobacter baumannii were subjected to the ceftazidime-2- mercaptoethanol -double-disk synergy test and to the PCR assays with primers specific for bla(IMP-1). After the process of sequencing the positive one to identify the results, PCR analysis was conducted with primers specific for class 1 integrons. For synergy test, 28 isolates gave positive results, among which were 27 Pseudomonas aeruginosa and Acinetobacter baumannii. Only one Pseudomonas aeruginosa was found to carry bla(IMP-1), and bla(Int1) at the same time. This is the first ascertainment of IMP-1 producing Pseudomonas aeruginosa isolate carrying bla(IntI1) in West China, which is of significance to the research on the clinical spread of these drug-resisitant genes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Pseudomonas aeruginosa
/
Beta-Lactamases
/
Microbial Sensitivity Tests
/
Ceftazidime
/
Imipenem
/
Drug Resistance, Multiple, Bacterial
/
Acinetobacter baumannii
/
Fermentation
/
Genetics
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS