The application of Atricure bipolar radiofrequency system in ablation of different parts and different times of pig heart atrium and the analysis of transmural lesions / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the transmural lesions of different parts of the pig heart atrium received different times of ablation applied with Atricure bipolar radiofrequency system.</p><p><b>METHODS</b>Six fresh (ex vivo time<20 min) pig hearts with atrium preserved intact were used as the experimental objects and experimental groups were divided according to the ablation position. The Atricure bipolar radiofrequency system was applied in the ablation of the parts of the atrium, such as posterior wall of left atrium, anterior wall of left atrium, anterior wall of right atrium and posterior wall of left atrium close to mitral posterior ring. Ablate the position of the atrium lengthened about 2.0 cm with the same thickness with an interval of 0.5 cm for 4 times respectively, also recording the time of every ablation. For each part and each time of ablation, the ablated atrial tissue was preserved with 4% formaldehyde and 5% glutaraldehyde, and was sent for observation under light microscope and transmission electron microscope. The ablation time and lesion were analyzed statistically.</p><p><b>RESULTS</b>In the same position of the atrium, ablation time decreased with the times of the ablation, in different position of the atrium with same time of ablation, time showed a positive proportion with the thickness of the atrium.</p><p><b>CONCLUSIONS</b>Atricure bipolar radiofrequency system is very safe and efficient, also convenient for manipulation. With regard to the relatively thinner part of the atrium, such as posterior wall and anterior wall of left atrium, at least two times of ablation can ensure transmural lesion of the atrial tissue, but to the position of the atrium such as anterior wall of right atrium and posterior wall of left atrium close to mitral posterior ring, 3 to 4 times of ablation can ensure transmural lesion of the atrial tissue.</p>