Study on preparation process and stability of beta-cyclodextrin inclusion compound in volatile oil of Cinnamomum longepaniculatum leaves / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2105-2108, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-346433
ABSTRACT
To study the optimum preparation process and stability of beta-cyclodextrin inclusion compound in volatile oil of Cinnamomum longepaniculatum leaves. The saturated aqueous solution method was adopted to prepare inclusion compounds for an orthogonal test. The inclusion compound productivity and the inclusion rate were taken as indexes for screening the inclusion processes. The inclusion effect was evaluated with the infrared spectrophotometry and TLC, and the stability under conditions of high temperature, high humidity and strong light was detected. Under optimum preparation conditions for inclusion, the ratio between volatile oil and beta-cyclodextrin was 1 8 (mL g), that between beta-cyclodextrin and water was 1 15, the inclusion temperature was 40 degrees C, and the inclusion time was 3 h. The results of spectrophotometry and TLC showed that the optimum conditions can generate beta-cyclodextrin inclusion compound in volatile oil of C. longepaniculatum leaves with certain light resistance, thermo-stability and hygro-stability. Therefore the optimum inclusion process features simple operation and stable inclusion compounds.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spectrophotometry, Infrared
/
Oils, Volatile
/
Chemistry
/
Chromatography, Thin Layer
/
Technology, Pharmaceutical
/
Plant Leaves
/
Cinnamomum
/
Beta-Cyclodextrins
/
Drug Stability
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
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