Etiological analysis on ocular fungal infection in the period of 1989 - 2000 / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 598-600, 2004.
Article
in English
| WPRIM
| ID: wpr-346621
ABSTRACT
<p><b>BACKGROUND</b>This study was to review the distribution and shifting trend of fungal of culture specimens isolated from eyes of patients at the Beijing Institute of Ophthalmology, Tongren Hospital, Beijing, China.</p><p><b>METHODS</b>The fungal culture-positive rate, the distribution and change of isolates of 2609 specimens collected in a 12-year period (1989 - 2000) were retrospectively analyzed.</p><p><b>RESULTS</b>In 775 positive cultures, 707 specimens (91.2%) were from the cornea, 22 (2.8%) from the conjunctiva, 15 (1.9%) from the anterior chamber, 9 (1.2%) from the vitreous body, 3 (0.4%) from the lacrimal sac, and 19 (2.5%) from other parts of the eye. The average culture-positive rate was 29.7%. The ratio of the positive cultures in the first half year (from January to June) to those in the second half (from July to December) was 12.1. The main genus cultured was Fusarium sp (58.7%), followed by Aspergirum sp (16.8%). The percentage of Fusarium sp was increased from 53.6% (1989 - 1994) to 60.2% (1995 - 2000), whereas the percentage of Aspergirum sp was decreased from 22.3% (1989 - 1994) to 15.1% (1995 - 2000).</p><p><b>CONCLUSIONS</b>Fusaruim sp is one of the most predominant pathogens of ocular fungal infection in northern China and its incidence tends to increase, but that of Aspergirum sp to decrease. It is very important to recognize the distribution and shifting trend of pathogenic fungi in the diagnosis, prevention and treatment of fungal keratitis.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aspergillus
/
Time Factors
/
Eye Infections, Fungal
/
Retrospective Studies
/
Fusarium
Type of study:
Etiology study
/
Observational study
Limits:
Humans
Language:
English
Journal:
Chinese Medical Journal
Year:
2004
Type:
Article
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