Relationship of concentration of lactoferrin and lysozyme in saliva and dental caries in primary dentition / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 82-84, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-346766
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between the concentrations of lactoferrin and lysozyme in saliva and dental caries in primary dentition among Chinese children.</p><p><b>METHODS</b>Forty children with high dmft score (dmft > or = 5) and 40 caries-free children (dmft = 0) were sampled and assigned into two groups. Total salivary proteins was measured by means of bicinchoninic acid. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) was performed to analyze the images of target straps. Lactoferrin and lysozyme were detected using Western blotting method.</p><p><b>RESULTS</b>The total salivary protein in high dmft group [(852.02 +/- 206.14) mg/L] was lower than that of caries-free group [(1032.44 +/- 221.99) mg/L, P < 0.001]. The ratio of 77,000 protein in high dmft group [(12.50 +/- 7.73) IA/microg] was significantly higher than that of the caries-free children [(8.71 +/- 4.28) IA/microg, P = 0.009], while there was no significant difference for 14,500 protein between them (P = 0.137). The ratio of lactoferrin was higher in high dmft group [(229.04 +/- 197.14) IA/microg] than that in caries-free children [(144.07 +/- 99.91) IA/microg, P = 0.018], while no significant difference for lysozyme between the two groups (P = 0.091).</p><p><b>CONCLUSIONS</b>Saliva protein is closely related to caries in primary dentition. Lactoferrin may be one of the important components.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Saliva
/
Salivary Proteins and Peptides
/
Tooth, Deciduous
/
Muramidase
/
Case-Control Studies
/
Chemistry
/
Epidemiology
/
Prevalence
/
Dental Caries
/
Lactoferrin
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Child, preschool
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2009
Type:
Article
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