Subchondral bone in osteoarthritis: a review / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 702-704, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-347089
ABSTRACT
Osteoarthritis (OA) is the most prevalent of joint diseases,and its pathology is characterized by the degeneration of cartilage, sclerosis of subchondral bone, and osteophyte formation. Localization of the early lesions of OA has not been clarified, but many researchers have focused on cartilage and have considered that changes in subchondral bone occur subsequently to the degeneration of cartilage. However, a low bone mineral density, particularly in the knee joint with OA, high bone turnover, and efficacy of bone resorption inhibitors for OA have recently been reported, suggesting that subchondral bone plays an important role in the pathogenesis of OA. This review aims to make a conclusion about advancement in research of subchondral bone in osteoarthritis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoarthritis
/
Pathology
/
Bone and Bones
/
Cartilage
/
Bone Remodeling
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS