Survival analysis of stage IV metastatic gastric cancer patients treated with HangAm-Plus / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 49-55, 2014.
Article
in English
| WPRIM
| ID: wpr-347182
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy of HangAm-Plus (HAP) on stage IV metastatic gastric cancer by analyzing the treated patients' overall survival outcome.</p><p><b>METHODS</b>Following the study eligibility, overall survival and one year survival rate of 44 stage IV metastatic gastric cancer patients who visited East-West Cancer Center (EWCC) were analyzed. The study consisted of two arms HAP treatment only (n=18) and combined treatment of concurrent conventional chemotherapy and HAP (n=26). Patient characteristics by gender, age, surgical intervention, Eastern Cooperative Oncology Group (ECOG) score, treatment duration (< 4 weeks or [Symbol see text]4 weeks), and lines of the chemotherapy received were assessed. Treatment related side effects were also assessed.</p><p><b>RESULTS</b>The median survival of combined group was longer (10.0 months) than that of HAP group (5.1 months). One-year survival rate of combined treatment group and HAP group was 38.5%±9.5% and 33.3%±11.1%, respectively (P>0.05). One-year survival rate of those received more and less than 4-week treatment was 57.1%±18.7% and 8.3%±8.0%, respectively (P=0.001).</p><p><b>CONCLUSIONS</b>The study supports the safety and potential efficacy of HAP treatment in prevention of chemo-related side effects for stage IV metastatic gastric cancer treated with conventional chemotherapy. Further studies are needed to investigate and confirm the results before applying the treatment in clinical settings.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Stomach Neoplasms
/
Drugs, Chinese Herbal
/
Survival Analysis
/
Therapeutic Uses
/
Drug Therapy
/
Neoplasm Metastasis
/
Neoplasm Staging
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese journal of integrative medicine
Year:
2014
Type:
Article
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