Orthokeratinized odontogenic cyst: a clinicopathological and immunocytochemical study / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinicopathological features and behavior of a group of jaw cysts with a solely orthokeratinized lining epithelium.</p><p><b>METHODS</b>20 cases of this cyst type were reported under the term of orthokeratinized odontogenic cyst (OOC) and their clinical, histological and immunocytochemical features were compared with that of odontogenic keratocyst (OKC).</p><p><b>RESULTS</b>The cysts of the present series were all solitary lesions, occurred mostly in young male patients, and showed a predilection for the posterior mandible areas. Follow-up of 15 patients revealed no recurrence following enucleation. Histological and immunocytochemical studies indicated that OOC epithelium lacked the typical features of OKC and appeared to show a lower proliferative activity.</p><p><b>CONCLUSION</b>These findings suggest that OOC is clinicopathologically distinctive from OKC and may thus constitute its own clinical entity.</p>