Detection of hepatitis C virus antibody in saliva and its clinical significance / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 449-451, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-347329
ABSTRACT
<p><b>OBJECTIVE</b>To detect hepatitis C virus (HCV) antibody in saliva and find its clinical significance.</p><p><b>METHODS</b>Sera and saliva samples from eighty-six patients were parallely detected HCV antibodies (anti-HCV) with EIA using a modified protocol.</p><p><b>RESULTS</b>Twenty-nine of 86 patients were positive for anti-HCV in sera samples; and, 27/29 were also anti-HCV positive with saliva samples. For the 57 anti-HCV negative sera, the saliva samples were all negative. Comparing with the results of sera, the sensitivity (93.1%, 27/29) and specificity (100%, 57/57) of salivary detection for anti-HCV could be accepted.</p><p><b>CONCLUSION</b>If the results of sera are considered as "golden standard", these results suggest that tests on saliva can be useful in HCV clinical diagnosis and epidemiological studies for estimating the prevalence of HCV in populations.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Saliva
/
Virology
/
Blood
/
Immunoenzyme Techniques
/
Sensitivity and Specificity
/
Hepatitis C
/
Hepacivirus
/
Clinical Laboratory Techniques
/
Diagnosis
/
Allergy and Immunology
Type of study:
Diagnostic study
/
Practice guideline
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2002
Type:
Article
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