Oral combination chemotherapy of 5'-deoxy-5-fluorouridine (furtulon) and cyclophosphamide for advanced breast cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 282-284, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-347441
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of the oral combination chemotherapy of furtulon (FTL) and cyclophosphamide (CTX) for advanced breast cancer (ABC).</p><p><b>METHODS</b>From Jun 2000 to Jun 2002, eighty-three patients with ABC were treated with the two oral drugs as combined chemotherapy. The mean number of cycles was 5, median number of cycles was 6 (range 2-6).</p><p><b>RESULTS</b>The overall response rate was 45.8%, The median time to progression was 6 months. The treatment was well tolerated, with related Grade 3 clinical adverse effect being only nausea and vomiting in 2 patients (2.4%) and mild hematologic toxicities.</p><p><b>CONCLUSION</b>Oral combined chemotherapy of FTL and CTX, being convenient and safe, is effective for patients with advanced breast cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast Neoplasms
/
Antineoplastic Combined Chemotherapy Protocols
/
Administration, Oral
/
Floxuridine
/
Cyclophosphamide
/
Therapeutic Uses
/
Drug Therapy
Limits:
Adult
/
Aged
/
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2003
Type:
Article
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