Prognostic factors of epithelial ovarian cancer in young women / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 264-267, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-347446
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the clinical characteristics, survival rate and prognosis of young patients with epithelial ovarian carcinoma.</p><p><b>METHODS</b>The clinic data of 455 women with epithelial ovarian carcinoma were reviewed. Kaplan-Meier method was used to calculate the survival rate. Cox proportional hazards regression model was used to determine the independent effect of each variable on survival.</p><p><b>RESULTS</b>Of 445 patients with epithelial ovarian carcinoma, 92 were < or = 40 years of age and 363 were older. Higher incidence of early-stage, well differentiation and mucous cell type but lower incidence of serous cell type, ascites and residual tumors were found in the younger group. The overall 5-year survival rates were 79.55% in < or = 40 years group and 28.2% in > 40 years group (P < 0.001). Univariate analysis showed that the survival rate of patients < or = 40 years was significantly higher than that of > 40 years. Only age, stage and residual disease were found to be the significant independent prognostic factors by the multivariate analysis.</p><p><b>CONCLUSION</b>Epithelial ovarian carcinoma in patients with age </= 40 has higher incidence of early stage, well differentiation and mucous cystadenocarcinoma as well as a higher 5-year survival rate but lower possibility of residual tumor and ascites. Stage, residual tumor size and age are independent prognostic factors of epithelial ovarian carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Pathology
/
Prognosis
/
Therapeutics
/
Proportional Hazards Models
/
Survival Rate
/
Mortality
/
Age Factors
/
Neoplasms, Glandular and Epithelial
/
Neoplasm Staging
Type of study:
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2003
Type:
Article
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