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Relationship between the endothelial barrier and vascular permeability after burns and its mechanism / 中华烧伤杂志
Chinese Journal of Burns ; (6): 324-326, 2007.
Article in Chinese | WPRIM | ID: wpr-347682
ABSTRACT
Massive burn trauma is characterized by hypovolemic shock induced by the loss of plasma from vessels. The major reasons for this systemic microvascular leakage in burns include an increase in vascular permeability triggered by inflammatory mediators and the increase of vascular hydrostatic pressure caused by vessel dilation. The maintenance of normal vascular permeability depends on the integrity of endothelial barrier function regulated by the interaction of intracellular junctions, cell-matrix adhesion and the cytoskeleton contractile force. This review summarizes some recent discovery in endothelial mechanisms during burn-induced vascular hyperpermeability.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Cytoskeleton / Myosin-Light-Chain Kinase / Burns / Capillary Permeability / Endothelium, Vascular / Actins / Rho-Associated Kinases / Metabolism Limits: Humans Language: Chinese Journal: Chinese Journal of Burns Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Cytoskeleton / Myosin-Light-Chain Kinase / Burns / Capillary Permeability / Endothelium, Vascular / Actins / Rho-Associated Kinases / Metabolism Limits: Humans Language: Chinese Journal: Chinese Journal of Burns Year: 2007 Type: Article