Efficacy of thromboelastography to monitor the clinical massive transfusion in scoliosis: a randomized controlled trial / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To systematically assess the benefits and harms of a thromboela-stogram (TEG) guided transfusion strategy with severe bleeding.</p><p><b>METHODS</b>In this prospective study, 60 patients scheduled for scoliosis were included in the Fourth Affiliated Hospital, Xinjiang Medical University, from May 2014 to February 2014.Patients were allocated into either an TEG group or a standard management group.</p><p><b>RESULTS</b>There was no significant difference in age, weight, height and operation time between the two groups (P>0.05). There were significant differences in red blood cell concentration((4.5±1.5)units and(7.1±1.2)units)(t=4.343, P=0.001), platelet((2.5±1.3)units and (4.2±0.6)units)(t=4.554, P=0.002), fresh frozen plasma((234±46)ml and(514±41)ml)(t=3.723, P=0.004), fibrinogen((2.4±0.6)g and (4.6±0.7)g)(t=3.451, P=0.006) between the TEG group and the standard management group.The two groups in intraoperative blood loss((1 023±103)ml and (1 314±116)ml)(t=2.260, P=0.120), incidence of rebleeding after operation(3.1% and 3.6%)(χ(2)=0.340, P=0.450), hospitalization time((18±4)d and (16±6)d)(t=2.140, P=0.160) had no statistically significant differences.</p><p><b>CONCLUSION</b>Application of a TEG guided transfusion strategy seems to reduce the amount of bleeding during correction operation of scoliosis.</p>