Effects of Several Biodegradable Controlled-Release Local Delivery Drugs on the Treatment of Periodontitis / 대한치주과학회지
The Journal of the Korean Academy of Periodontology
;
: 725-735, 1999.
Article
in Korean
| WPRIM
| ID: wpr-34934
ABSTRACT
The present study was performed to evaluate the clinical effects following local application of 30% minocycline strip(polycaprolactone), 2% minocycline gel(hydro-carbon gel) and 12% minocycline strip(polylactide, Minodent) to augment scaling and root planing in patients with chronic adult periodontitis. Forty teeth with periodontitis were enrolled in the study anddistributed into 4 groups including control group. All patients performed standardized oral hygiene instructions and mechanical debridement at the beginning of the study and then each local delivery drugs were inserted into periodontal pocket in each groups. Examinations regarding plaque index(PI), papillary bleeding index (PBI), probing pocket depth (PPD) were carried out at 0, 2, 4 weeks. All experimental groups showed statistically significant differences between baseline and 2 and 4 weeks in every clinical indices. Especially, 30%minocycline strip and Minodent group showed a significant improvement in PBI at 2 weeks and in PPD at 2 and 4 weeks. In conclusion, highly bio-resorbable Minodent delivered subgingivally as an adjunct to scaling and root planing induces better clinical effects for periodontal health than 2% minocycline gel and control group.
Full text:
Available
Index:
WPRIM (Western Pacific)
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Journal of the Korean Academy of Periodontology
Year:
1999
Type:
Article
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