Laggera pterodonta--a Yunnan Herbal Medicine / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 406-409, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-349432
ABSTRACT
OBJECTIVE:
A systematic study of Laggera pterodonta was performed in order to identify its bioactive compounds.METHODS:
Solvent partition and column chromatography used to isolate and purify Laggera pterodonta compounds. The isolated compounds were further elucidated by high field NMR spectroscopy.RESULTS:
Fifty-two compounds were separated and the structures of 39 compounds were elucidated. Twenty-four compounds have not been previously reported. For example, the structure of compound 19, a previously undetected compound was elucidated as 4gamma, 9alpha,11-triol-enantio-eudesmane using both 1D and 2D NMR spectroscopy. Major secondary metabolites of the Laggera pterodonta included eudesmane-type sesquiterpenes and flavone derivatives.CONCLUSION:
A systematic study of a yunnan herbal medicine Laggera pterodonta resvealed several novel compounds that may have clinical significance. Further in vivo animal studies should be performed to assess their bioactive role.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2002
Type:
Article
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