Determination of VMA/Cr and HVA/Cr in random urine collection for the diagnosis of neuroblastoma / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 219-221, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-349436
ABSTRACT
OBJECTIVE:
To evaluate the VMA/Cr and HVA/Cr of random urine in the diagnosis of neuroblastoma.METHODS:
VMA/Cr and HVA/Cr were examined in 50 normal children and 11 cases of neuroblastoma (NB) aged 1 approximate, equals 5 years. The concentration of 4-hydroxy-3-methoxy-mandelic acid (VMA) and homovanillic acid (HVA) in random urine collection were analyzed by high-performance liquid chromatography and creatinine (Cr) analyzed by auto-biochemical analyzer.RESULTS:
The normal range of VMA/Cr and HVA/Cr were <14.9 mmol/mol and <23.8 mmol/mol, respectively. The positive rate of VMA/Cr and HVA/Cr in NB patients was 90.9%.CONCLUSION:
Determination of VMA/Cr and HVA/Cr in random urine collection can be used for NB diagnosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Diagnostic study
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2002
Type:
Article
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