Free alpha hCG--a serum marker for pregnancy-induced hypertension / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 210-211, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-349439
ABSTRACT
OBJECTIVE:
To evaluate the free alpha subunit of human chorionic gonadotropin (FalphahCG) as a marker for pregnancy-induced hypertension (PIH).METHODS:
The study group consisted of 74 pregnant women with hypertension. PIH admitted at 21-43 weeks of gestation. The control group was 37 non-PIH women. Serum FalphahCG was measured by radioimmunoassay with monoclonal technology. Using Youden's index of the receiver operator characteristic curve(ROC), a threshold value was determined.RESULTS:
FalphahCG levels in PIH women were significantly higher than in the control group women [(556+/-428)IU/L compared with (232+/-131)IU/L,P<0.001].Using 260 IU/L of FalphahCG as the threshold value yields a sensitivity of 81.1% and specificity of 75.7% with a Youden's index of 0.57 for predicting PIH.CONCLUSION:
Serum FalphahCG may serve as a useful marker to predict PIH.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2002
Type:
Article
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