A rare case of acute promyelocytic leukemia accompanied by benign craniopharyngioma / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 660-665, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-349652
ABSTRACT
The purpose of study was to analysis the clinical manifestation and treatment protocol of acute promyelocytic leukemia (APL) accompanied by craniopharyngioma so as to promote the understanding of this disease. The APL was diagnosed by morphologic examination of bone marrow cells, the leukemia bone marrow cells were analyzed by immunophenotyping technique, the qualitative and quantitative changes of PML-PARα fusion gene before and after treatment were monitored by using molecular biological test; the cytogenetic features were analyzed by using conventional karyotype and FISH analysis. The results indicated that the clinical manifestation of this disease was diverse and disease status was complex. The good therapeutic efficacy could be achieved, the misdiagnosis and delayed treatment could be avoided through early detection, timely treatment and multidisciplinary cooperation. It is concluded that when other clinical symptoms reappear after APL achieves remission, the possibility of second tumor must be considered, the clinical presentation should be carefully monitored, the early detection and timely treatment should be performed to improve the survival of patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pituitary Neoplasms
/
Leukemia, Promyelocytic, Acute
/
Craniopharyngioma
Type of study:
Practice guideline
/
Qualitative research
/
Screening study
Limits:
Humans
/
Male
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2014
Type:
Article
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