Prevalence of Tannerella forsythensis in subgingival plaque of type 2 diabetic patients / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 57-61, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-350237
ABSTRACT
<p><b>OBJECTIVE</b>To study the prevalence of Tannerella forsythensis (T. forsythensis) in the subgingival plaque of type 2 diabetes, analyze the relationship between Tforsythensis and related factors, discuss the role of T. forsythensis in the chronic periodontitis and type 2 diabetes.</p><p><b>METHODS</b>160 subgingival plaque samples were collected from type 2 diabetic patients and pathogens genomic DNA were extracted by phenol and chloroform from plaque. T. forsythensis was detected by polymerase chain reaction, and Pearson correlation and Logistic regression analysis were used to analyze the relationship between T. forsythensis and systemic factors and periodontal status.</p><p><b>RESULTS</b>The prevalence of T. forsythensis in mild, moderate, severe periodontitis group was 47.82%, 48.71%, 67.39% respectively, and the prevalence was higher in the severe periodontitis group than in mild, moderate group (P < 0.05). There was no T. forsythensis in 6 diabetic patients with healthy periodontium. Logistic regression analysis illustrated that the prevalence of T. forsythensis was associated with simplified oral hygiene index (OHI-S) and diabetic duration (OR = 1.947, OR = 0.873).</p><p><b>CONCLUSION</b>The prevalence of T. forsythensis in type 2 diabetes with chronic periodontitis was related with oral hygiene, periodontal status and diabetic duration.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Periodontitis
/
Bacteroides
/
Polymerase Chain Reaction
/
Prevalence
/
Porphyromonas gingivalis
/
Dental Plaque
/
Diabetes Mellitus, Type 2
/
Chronic Periodontitis
Type of study:
Prevalence study
/
Risk factors
Limits:
Aged
/
Humans
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2011
Type:
Article
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