Intratympanic methylprednisolone hemisuccinate injection in treating the refractory noise induced deafness / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 547-548, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-350544
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the efficacy of Methylprednisolone hemisuccinate intratympanic injection for refractory noise induced deafness.</p><p><b>METHODS</b>One hundred and twenty cases (215 ears) of noise induced deafness were treated with either hormone group (107 ears) or with non hormone group (108 ears). Following prior interventions, 145 ears went on to receive intratympanic Methylprednisolone hemisuccinate injection twice a week.</p><p><b>RESULTS</b>After Intratympanic therapy, the total effective rate was 46.2%. 32 of 71 ears (45.1%) demonstrated hearing improvement in hormone group and 35 of 74 ears (47.3%) in non hormone group. The difference was statistically insignificant (P = 0.788).</p><p><b>CONCLUSION</b>Intratympanic therapy appears to provide additional treatment benefits for patients with refractory noise induced deafness who have been treated with prior interventions. The outcome is not affected by pretreatment with hormone.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Methylprednisolone Hemisuccinate
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Injection, Intratympanic
/
Glucocorticoids
/
Hearing Loss, Noise-Induced
/
Hearing Tests
/
Noise
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Year:
2015
Type:
Article
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