A Study on Incidence and Genetic Background of Atopic Dermatitis / 대한피부과학회지

ABSTRACT

In atopic dermatitis, genetic factor undoubtedly involved, but precise mode of tra- nsmission is not yet clear. Since the true incidence and mode af transmission requires a large scale prospective study, they are very difficult to determine. This study was performed in order to elucidate incidence and hereditary backgro- und of atpoic dermatitis in the selected and secluded urban area where relatively an inbred population lived, because of substantially less immigration from other area. Investigation of this study were carried out among infants and children under 6 year old, The results were as follows 1) A total of 516 infants and children under 6 year nld were examined (male 267, female 249) 2) The incidence of atopic dermatitis was ll.2% (58/516). 3) 67. 3% of patients with atopic dermatitis (39/58) had a family history of atopic dermitis, urticaria and asthma. 4) Frequent clinical features of these patients were pruritus (93. 1%), dry or coarse skin (85. SF), and facial and extensor involvement of the skin (82.7%). 5) Molluscum contagisum (9 cases), impetigo(7 cases, strophuius (4 cases), and.. uzticaria (2 cases), were combined. with atopic dermatitis.