Relationship between aberrant expression of miRNAs and prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 657-661, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-350841
ABSTRACT
MicroRNAs (miRNAs) are a kind of small non-coding single-stranded RNA molecules that negatively regulate gene expressions by binding to imperfect complementary sites in the 3 untranslated region of targeted mRNAs at the post-transcriptional level. The aberrant expression of some miRNAs has been discovered to be involved in the pathogenesis of various cancers, including prostate cancer. By analyzing miRNA expressions in prostate cancer tissues, serum and cell lines, and then investigating their mechanisms, we expect to provide some new theoretic bases for the clinical diagnosis and treatment of prostate cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatic Neoplasms
/
RNA, Messenger
/
Gene Expression Regulation, Neoplastic
/
MicroRNAs
/
Genetics
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2013
Type:
Article
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