The anti-inflammation effects of Smilax china ethylacetate extract in rats and mice / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the anti-inflammations of the ethyl acetate extract of S. china on acute and chronic inflammations.</p><p><b>METHOD</b>The rat paw edema induced by egg-albumin, the ear edema and the foot edema of mice induced by xylene and formaldehyde, the increased vascular permeability of capillary induced by intraperitoneal injection of 0.7% acetic acid in mice were used to study on the acute, early inflammations and chronic inflammation for the ethyl acetate extract of S. china.</p><p><b>RESULT</b>The extract (50-100 g x kg(-1)) could significantly decrease the rat paw edema, and inhibit the ear edema, the increased vascular permeability and the foot edema of mice.</p><p><b>CONCLUSION</b>The ethyl acetate extract of S. china possesses remarkable anti-inflammatory effects on acute inflammation, and also displays anti-inflammatory effects on the chronic inflammation at a certain extent.</p>