Research on biological detoxification of Chinese medicine containing aristolochic acid A by ten microorganisms / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1939-1944, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-351235
ABSTRACT
This paper was aim to screen microorganisms with attenualed efficiency for Chinese medicine containing aristolochic acid A by liquid-state fermentation. Twelve Chinese medicine were detected by UPLC and aristolochic acid A was only founded in four species of Aristolochia, those were Caulis Aristolochiae Manshuriensis, Aristolochiae Radix, Aistolochia Contorta Bunge and Herba Aristolochiae Mollissima,but not in the others. With the four Chinese medicine containing aristolochic acid A as raw material, ten microorganisms were tested, and the content of aristolochic acid A was detected by UPLC. The results showed that one microorganism can decrease content of aristolochic acid A in all those four Chinese medicine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Bacteria
/
Drugs, Chinese Herbal
/
Biotransformation
/
Chemistry
/
Aristolochic Acids
/
Fungi
/
Metabolism
/
Microbiology
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article
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