Risk factors for poor prognosis in children with severe adenovirus pneumonia / 中国当代儿科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the risk factors for poor prognosis of severe adenovirus pneumonia (SAP) in children.</p><p><b>METHODS</b>The clinical data of 189 children with SAP were retrospectively analyzed. Univariate logistic regression analysis was performed to assess the risk factors for poor prognosis.</p><p><b>RESULTS</b>The univariate logistic regression analysis showed that the patients with hemoglobin <90 g/L, plasma albumin <30 g/L, C-reactive protein >30 mg/L, procalcitonin >10 ng/mL, alanine aminotransferase >100 U/L, or aspartate aminotransferase >100 U/L had poor prognosis (P<0.05), and that those with congenital dysplasia of the airway, acute respiratory distress syndrome, circulatory complications, electrolyte and acid-base disturbance, or more than three complications also had poor prognosis (P<0.05).</p><p><b>CONCLUSIONS</b>Poor prognosis of severe adenovirus pneumonia in children is associated with anemia, low serum albumin, inflammatory response, concurrent multiple complications and underlying lung diseases.</p>