Chemical constituents from Viscum nudum and their accelerating PC12 cell differentiation / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1340-1342, 2006.
Article
in Zh
| WPRIM
| ID: wpr-351748
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate chemical constituents of the stem of Viscum nudum and their bioacyivity.</p><p><b>METHOD</b>The major chemical constituents were isolated from the AcOEt-solved part of ethanol-extract of the plant by column chromatography and the active screening test in vitro were taken out for looking for compounds to acccelerate PC12 cell differentiation.</p><p><b>RESULT</b>5 compounds were identified as eriodictyol (1), 5, 7-dihydroxy-3', 4'-dimethoxy flavanone (2), oleanolic (3), 5, 7-dihydroxychromone (4) and homeriodictyol (5) by spectral evidences, in which homeriodictyol (5) had acceleration differentiation to PC12 cell.</p><p><b>CONCLUSION</b>All compounds were obtained from this plant for the first time, and bioactive constituent was observed in the AcOEt-solved part.</p>
Full text:
1
Index:
WPRIM
Main subject:
Oleanolic Acid
/
Pharmacology
/
Plants, Medicinal
/
Cell Differentiation
/
Chemistry
/
Chromones
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PC12 Cells
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Plant Stems
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Viscum
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Cell Biology
Limits:
Animals
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Type:
Article