Effects of Siwu Tang on protein expression of HFCL / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1083-1086, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-351840
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of Siwu Tang on HFCL proliferation and protein expression of bone marrow stromal cells and to discuss molecular mechanism of enriching blood functions of Siwu Tang.</p><p><b>METHOD</b>MTT, flow cytometry and proteomics were used respectively to measure the effect of Siwu Tang on HFCL proliferation, cell cycle and proteinexpression.</p><p><b>RESULT</b>Siwu Tang can promote HFCL proliferation, increase proliferative index, up-regulate 12 kinds of proteins and down-regulate 5 kinds of proteins of HFCL.</p><p><b>CONCLUSION</b>Through promoting HFCL proliferation and acting on multipleprotein targets, the blood enriching function of Siwu Tang was exerted indirectly.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Plants, Medicinal
/
Bone Marrow Cells
/
Drugs, Chinese Herbal
/
Proteins
/
Cell Cycle
/
Cell Line
/
Chemistry
/
Fibroblast Growth Factor 2
/
Stromal Cells
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Type:
Article
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