Special morphological changes of pathologic cells in two cases of Waldenström's macroglobulinemia / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 220-223, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-352094
ABSTRACT
Waldenström's macroglobulinemia (WM) is one of malignant hematological disease on account of abnormal proliferation of B lymphocyte clone and the pathologic cells of WM possess ability to secrete monoclonal immunoglobulin M. In this study, the diagnosis and morphological characteristics of 2 patients with WM were analyzed. The results showed that a special kind of "foam cells" were found by cytochemical staining examinations in both cases, which displayed characteristics of lymphocytes, but neither monocyte-macrophage nor fatty cells. The periodic acid-Shiff's reaction (PAS) demonstrated strong positive, especially on the inclusion bodies in pathologic cell plasma while the acid phosphatase, and alpha-butanoic acetate esterase stainings, resulted both in negative. In conclusion, the cells found in the two cases reported may be described as gemmy ring-like lymphocyte in morphology, a special subtype of ring-like lymphocyte.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Waldenstrom Macroglobulinemia
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2004
Type:
Article
Similar
MEDLINE
...
LILACS
LIS