Three biflavonoids from ethanol extract of the root of Daphne genkwa / 药学学报
Acta Pharmaceutica Sinica
;
(12): 438-442, 2005.
Article
in English
| WPRIM
| ID: wpr-353439
ABSTRACT
<p><b>AIM</b>To investigate the chemical constituents of the secondary metabolites of the roots of Daphne genkwa.</p><p><b>METHODS</b>The roots of D. genkwa were extracted with 95% ethanol at 60-70 degrees C for 7 days to obtain the crude extract. The crude extract was purified by silica gel and Sephadex LH-20 column chromatography as well as the HPLC techniques. The structures of the isolates were elucidated by combined spectroscopic methods including 1D and 2D NMR, MS, UV, IR and CD.</p><p><b>RESULTS</b>Three new biflavonoids were isolated from the ethanol extract of the roots of D. genkwa and their structures were identified as daphnodorin H-3-methyl ether (1), daphnodorin H-3"-methyl ether (2) and daphnodorin G-3"-methyl ether (3).</p><p><b>CONCLUSION</b>Compounds 1, 2 and 3 are three new biflavonoids.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Molecular Structure
/
Chemistry
/
Plant Roots
/
Daphne
/
Biflavonoids
/
Ethanol
/
Molecular Conformation
Language:
English
Journal:
Acta Pharmaceutica Sinica
Year:
2005
Type:
Article
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