Intravaginal desensitization in a woman with seminal fluid allergy / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 518-523, 1998.
Article
in Korean
| WPRIM
| ID: wpr-35395
ABSTRACT
Human seminal fiuid (HSP) hypersensitivity is rare, but possibly a life-threatening disease. The pathogenesis of seminal plasma hypersensitivity and the exact nature of the HSP allergens remains to be clarified. We report a case of 25-year-old female patient who complained of severe itching sensation, flushing and edema of external genitalia, facial edema and dyspnea after sexual intercourse. The diagnosis was established by skin pr ick test with her husbands diluted semen. Intravaginal desensitization was performed by modified Matloffs method. Dilutions was made with sterile human serum albumin(0.2%) and 0.4% pheno1-0.9% saline solution. Two ml each of progressively greater concentrations of semen dilutions(1 100,000 v/v, 1 10,000 v/ v, 11,000 v/v, 1100 v/v, 110 v/v) were inserted intravaginally at 45-min intervals, followed by an undiluted specimen. The patient was successfully desensitized and could have unprotected intercourse without anaphylaxis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pruritus
/
Semen
/
Sensation
/
Skin
/
Allergens
/
Sodium Chloride
/
Coitus
/
Spouses
/
Diagnosis
/
Dyspnea
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Journal of Asthma, Allergy and Clinical Immunology
Year:
1998
Type:
Article
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