Coexpression of Schwann cell marker GFAP and myoepithelial cell marker alpha-SMA in salivary adenoid cystic carcinoma / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 461-463, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-354344
ABSTRACT
<p><b>OBJECTIVE</b>To observe the expression of Schwann cell marker GFAP and myoepithelial cell marker alpha-SMA in salivary adenoid cystic carcinoma (ACC), and to evaluate the relationship of GFAP, alpha-SMA and perineural invasion in ACC.</p><p><b>METHODS</b>Immunohistochemical SABC method, double-label immunofluorescence and CLSM were used to detect the expression of GFAP and alpha-SMA proteins in salivary ACC tissue samples.</p><p><b>RESULTS</b>In salivary ACC tissue samples, both GFAP and alpha-SMA proteins were positive, which were coexpressed in cytoplasm of the same onco-myoepithelial cells.</p><p><b>CONCLUSIONS</b>There may be Schwann cell differentiation in onco-myoepithelial cell of salivary ACC, and it may be the pathological base of perineural invasion in salivary ACC.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Schwann Cells
/
Salivary Gland Neoplasms
/
Actins
/
Carcinoma, Adenoid Cystic
/
Muscle Cells
/
Epithelial Cells
/
Glial Fibrillary Acidic Protein
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2006
Type:
Article
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