Q Fever as a Cause of Acute Hepatitis Accompanying Fever / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 189-193, 2011.
Article
in Korean
| WPRIM
| ID: wpr-35464
ABSTRACT
Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently. Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis. Herein, we report 4 cases of acute Q fever as a cause of acute hepatitis and fever. All patients had fever and non-specific symptoms, and laboratory test showed acute hepatitis. Antibody surveys for many virus infections and bacterial cultures were negative. Finally, they were diagnosed acute Q fever by an indirect microimmunofluorescence test. Liver biopsy in 3 patients revealed granuloma including one with typical fibrin-ring. All patients had complete resolution of symptoms and signs with doxycycline treatment. Q fever should be considered in the differential diagnosis of patients with fever of unknown origin with acute hepatitis in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Q Fever
/
Rifampin
/
Acute Disease
/
Coxiella burnetii
/
Doxycycline
/
Fluorescent Antibody Technique, Indirect
/
Hepatitis
/
Anti-Bacterial Agents
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2011
Type:
Article
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